Vildagliptin Impurity 5 CAS 1789703-37-2(free base)
| CAS No. | 1789703-37-2(free base) |
| Molecular Formula | C17H25N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Vildagliptin Impurity 5 (CAS 1789703-37-2(free base), C17H25N3O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Vildagliptin Impurity 5 (C17H25N3O2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Vildagliptin Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H25N3O2 HCl |
| Molecular Weight | 339.86 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Vildagliptin Standards
- Vildagliptin Impurity 7 (CAS 1032564-18-3)
- Vildagliptin Impurity 2 (CAS 1036959-23-5)
- Vildagliptin (2R)-Isomer (CAS 1036959-27-9)
- Vildagliptin-13C5,15N (CAS 1044741-01-6)
- Vildagliptin Impurity 64 (CAS 105-48-6)
- Vildagliptin-d7 (CAS 1133208-42-0)
- Vildagliptin ß-D-Glucuronide (CAS 1147403-03-9)
- Vildagliptin Impurity 60 (CAS 1211679-98-9)
Recommended Standards
- (E)-Ramelteon Impurity 11 (CAS 196597-61-2)
- Progesterone Impurity 95 (CAS CATO-C4X-150295)
- Spiramycin EP Impurity G (CAS CATO-C4X-23256)
- 4-{5-[(4-methylpiperazin-1-yl)methyl]-1,3-thiazol-2-yl}morpholine (CAS 439121-13-8)
- 3-((Furan-2-ylmethylene)amino)oxazolidin-2-one (CAS 6270-33-3)
- N1-Cyclopentyl-N2-(3-phenylpropyl)oxalamide (CAS 941980-11-6)
- 4-Azidocinnamaldehyde (CAS 22736-78-3)
- 4-Amino-6-methyl-4,5-dihydro-1,2,4-triazin-3(2H)-one hydrochloride (CAS 158329-07-8)
- Levofloxacin impurity 73 (CAS CATO-C4X-137173)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com